Participation and Examinations
The ORCHESTRA Luxembourg study is formed as a subgroup of the Luxembourg Parkinson’s Study. Through this new study, people with Parkinson’s disease (PD) and healthy controls are kindly invited to support research on COVID-19 in relation to PD, in Luxembourg and the Greater Region. Participation in this study is very important as the SARS-CoV-2 first appeared in 2019 and thus has not been studied extensively yet, which is required to better predict future pandemic outbreaks and their consequences. Study-based evidence allows developing recommendations for effective prevention, protection and optimised treatment of COVID-19 patients.
What does the participation entail?
- A questionnaire (which takes approximately 30 minutes) that addresses the following domains:
- Demographic and socio-economic questions
- Comorbidities (i.e. other diseases besides PD) and current medication
- SARS-CoV-2 vaccine
- Knowledge and perception of risks related to SARS-CoV-2
- Questions related to Parkinson’s disease
- Psychological questions
- Collection of biological samples: blood, a nasal and a throat swab. In addition, a stool sample will be collected on a voluntary basis.
For the sample collection a nurse will visit you at home.
Specific tests are foreseen on the samples, e.g.:
- Virology testing on nasopharyngeal samples to check if the virus is present and which virus variant.
- Serology testing on blood samples to analyse the antibodies circulating in the blood indicating if the immune system encountered and reacted against the coronavirus and/or the vaccine.
To achieve long-term monitoring and understand the long-term effects, this procedure will be repeated at 3, 9, and 21 months. By offering a little bit of your time across the next two years, you can make an important contribution to understanding how well people with PD specifically are protected from COVID-19 by getting vaccinated.
To participate, please contact: orchestra.luxembourg [at] lih.lu